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  (#76) Old
Newbie geek
palekids head weighs 8lbs
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25-10-08, 02:48 PM

hiyaa u say that theres a massive increase of freckles? cz i actually have quite alot of freckles on my face nd i wear make up to cover them up cz i h8 them! thats i actually want these injections to make me brown nd to cover up my freckles more!! does this nt happen? x
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  (#77) Old
Newbie geek
icclestaces head weighs 8lbs
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Location: Rochdale
Melanotan 2 - 27-10-08, 11:09 AM

Its normally 35 per course and the course takes about 20 days to complete if you have 0.1mg every other day and 2-3 sunbed sessions you then have a fab natural tan that should fade in about 2 months, if you want to keep up the tan buy another bottle and have 1 injection per week for maintenence. I am using melanotan 2 and have a great tan> i had a a hot flush that lasted about 2 mins with my first injection and felt slightly nausious but was fine afterwards and i have a few more freckles. it seems to tan men a lot faster and darkens facial hair but only in men due to testoterone levels. it is proven to reduce skin cancer by 50% as the best defence against skin cancer is a natural tan. i used a course before my holiday and i am fair skinned and i went really dark and diddnt burn at all and only used a factor 8 and kept the holiday tan for 3 months. The drug is now in phase 3 of research and is legal to take for research purpose only and at the users own risk. Insulin needles are used and the injection is completly painless.I inject into the sides of my tummy away from the belly button, you can also use top of thigh or buttox anywhere flabby/fleshy. the injection is subcut so does not go into the muscle and shoulnt leave and blood or marks. it was a bit wierd injecting my self but i was fine with it after doing my first 1 but it isnt for everyone. it is available as a nasal spray but more side effects with this and more expensive> My friend has ginger hair and has never tanned but is now lovley and golden with melanotan 2
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  (#78) Old
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icclestaces head weighs 8lbs
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Location: Rochdale
27-10-08, 11:23 AM

in the first week you get an increase in freckles, when you actually start to get brown the freckles go away x
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  (#79) Old
Geeky
 
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drew692 is a lumberjack and he's okay!drew692 is a lumberjack and he's okay!
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Location: Bedford
27-10-08, 05:08 PM

Im a curly ginger (well originally lol) with the typical pale and frecklie skin, Im like a vampire in the sun, I dont tan, but I like a tan, but I'd only ever have a spray tan because sometimes I like to be pale and interesting too.

I couldnt inject myself with tan I think thats just too scary, but I guess thats what people first thought about Botox.
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  (#80) Old
Geeklette
 
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27-10-08, 07:36 PM

Quote:
Originally Posted by drew692 View Post
Im a curly ginger (well originally lol) with the typical pale and frecklie skin, Im like a vampire in the sun, I dont tan, but I like a tan, but I'd only ever have a spray tan because sometimes I like to be pale and interesting too.

I couldnt inject myself with tan I think thats just too scary, but I guess thats what people first thought about Botox.


The needle is 5mm = very tiny. Given to diabetics to inject themselves with insulin.

Im currently on injection number 5.. im so excited to see how it all turns out. Its very painless but i couldnt inject myself either so i get my fiance to do it for me

When ive had the full ten injections and the tan has appeared, how do i maintain the tan? Is the only option to inject once a week? Also ive not gone on the sunbed as of yet.. would you recomend this? Does it bring the tan out any faster?

xx
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  (#81) Old
Geeklin
Melanotans head weighs 8lbs
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Join Date: Oct 2008
Location: California
Inform yourself well about the melanotan peptides! - 28-10-08, 01:40 PM

Quote:
Originally Posted by icclestace View Post
it is proven to reduce skin cancer by 50% as the best defence against skin cancer is a natural tan. i used a course before my holiday and i am fair skinned and i went really dark and diddnt burn at all and only used a factor 8 and kept the holiday tan for 3 months. The drug is now in phase 3 of research and is legal to take for research purpose only and at the users own risk.
First and foremost, neither peptide (Melanotan one or Melanotan II) has been demonstrated to prevent skin cancer or reduce skin cancer rates. Only Melanotan one has been demonstrated in human trials to reduce by 50% sun (UV) damage to the skin (damage reduction primarily stemming from the melanin that folks are able to generate with it). It is quite likely that such photoprotective damage reduction prevents cancer, but there is ZERO SCIENTIFIC PROOF of that.
While it has been shown that those who develop a natural tan slowly over weeks (ie: through working outside and getting natural sun exposure) tend to have low skin cancer rates this is also true of those who avoid UV exposure all together. Also, neither peptide has been approved by any drug regulatory agency anywhere for usage in humans outside of human trials.

Unfortunately there is some confusion about melanotan one and melanotan II. Melanotan one is the version of the peptide that has been trialed in humans (both men & women) and studied extensively for tanning (pull up the Wikipedia article about it). Melanotan one is the version that is being developed in Australia by Clinuvel as a photoprotective agent (under the name "afamelanotide"). Melanotan II has been studied for safety as well and scientifically demonstrated to cause melanogenesis (melanin generation) in skin but it has primarily been studied as an anti-sexual dysfunction drug (because it increases desire/libido in women and men and overcomes erectile dysfunction in men). Melanotan II has only had a few human trials done with it and only in men.

While it is likely the case that in terms of tanning everything that has been demonstrated in melanotan one is true in melanotan II, nothing has been proven (ie: melanotan II hasn't been scientifically demonstrated to reduce sun (UV) damage). While this is true there are a number of other effects of Melanotan II besides tanning that just haven't been studied to the extent that melanotan one has been studied (in terms of tanning). It is likely the case that both peptides are equally safe to use but ONLY melanotan one has been scientifically studied and trialed in humans to a significant degree and of the two it is the only version that will likely ever be approved for usage in humans outside of human trials.

Folks should do their due diligence in fully learning about the peptides before ever considering using either one. The peptides work systemically (across all of the body) and once a tan develops in the skin while using one of the them it can take some time before it fades back to the shade of one's skin prior to using it (in one study melanotan one users were reported to go back to normal levels after 11 weeks). Folks who are prone to get moles should be aware that taking either peptide is liable to make your moles darken and make moles that were essentially not-visible, visible. There have been people who have successfully had their moles removed by dermatologists and gone on to use the peptides successfully but there have also been people who were not aware of the possibility that their moles would darken who got discouraged about using a peptide after experiencing mole darkening while using one.
Optimally anyone considering getting a tan with melanotan one or melanotan II should have their skin examined by a dermatologist for any issues prior to taking either. Such an examination can likely be gotten for free or for a low charge under the guise of a, "skin cancer screening". These types of screenings can likely be covered through health care plans and/or national coverage. During such an examination people should inform themselves about tanning in general and how it can affect the skin.
Look around for FAQs about using the peptides and check other forums, inform yourself well and understand fully how the peptides work before ever using either one.

Thanks,

-Scott
Melanotan.org - afamelanotide Founder & Admin

Last edited by Melanotan; 23-09-09 at 06:28 AM. Reason: proper sig
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  (#82) Old
the only way is up...baby
 
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collin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocket
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28-10-08, 02:11 PM

Quote:
Originally Posted by Melanotan View Post
It is quite likely that such photoprotective damage reduction prevents cancer, but there is ZERO SCIENTIFIC PROOF of that.

While it has been shown that those who develop a natural tan slowly over weeks (ie: through working outside and getting natural sun exposure) tend to have low skin cancer rates this is also true of those who avoid UV exposure all together.
Melanotan.org Admin
Not wishing to go off topic to much I would never the less like to pick up on this point.

There was extensive research undertaken on a world wide basis a number of years ago concerning the issue of skin cancer rates relative to UV exposure.

The findings were conclusive that those exposed to UV over generations have less likelihood of skin cancer than those who dont have a regular exposure and then experience high dosage.(beach holiday etc)

The results indicate that equatorial inhabitants have a far less skin cancer rate than elsewhere in the world.

Indeed with the ozone layer scare some years back the Australians headed for cover and exposure to natural UV was basically nil.

Once the scare became something of a distant memory and individuals began to expose themselves to the sun again..the skin cancer rate rose again.
HTH
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  (#83) Old
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28-10-08, 06:44 PM

Sorry Collin but surely research shows increased skin cancers near the equator although not in darker skins! Can I see your evidence please?

And surely the Australians exposure to the sun could have caused the increase or a changing ozone layer?! There are too many factors involved to measure this! Those that have more exposure are more likely to have more melanin anyway so this does not surely relate to those with fairer skins who are more likely to try use a sun bed or use melanotan.

(this is a non-agressive posting )

Plus a quote "Black peoples skin produce more melanin, even in the absence of sunlight, and their type of melanin, eumelanin, is more effective at blocking solar rays. However, white skin produces melanin only in the presence of sunlight and after the UV rays have penetrated the lower portion of the epidermis and have caused skin damage."

Natural melanin already found naturally in the skin is a sun block however. A sun tan only offers a very small amount of protection but the sun damage causes more problems!

Does Melanotan produce Eumelanin or Pheomelanin? Or is this not important? I'm confused but know eumelanin is what is skin-protecting in darker skins.



Just re-read this and it sound like I'm waffling please excuse my chain of thought!

Just realised how much I begrudge the sun putting its hat on but at least he is slightly protected!

Last edited by weezie; 28-10-08 at 07:08 PM.
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  (#84) Old
the only way is up...baby
 
collin's Avatar
collin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocketcollin says folks don't laugh so loud when you got a grand in your pocket
Posts: 5,315
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28-10-08, 07:47 PM

Quote:
Originally Posted by weezie View Post
Sorry Collin but surely research shows increased skin cancers near the equator although not in darker skins! Can I see your evidence please?

And surely the Australians exposure to the sun could have caused the increase or a changing ozone layer?! There are too many factors involved to measure this! Those that have more exposure are more likely to have more melanin anyway so this does not surely relate to those with fairer skins who are more likely to try use a sun bed or use melanotan.

(this is a non-agressive posting )

Plus a quote "Black peoples skin produce more melanin, even in the absence of sunlight, and their type of melanin, eumelanin, is more effective at blocking solar rays. However, white skin produces melanin only in the presence of sunlight and after the UV rays have penetrated the lower portion of the epidermis and have caused skin damage."

Natural melanin already found naturally in the skin is a sun block however. A sun tan only offers a very small amount of protection but the sun damage causes more problems!

Does Melanotan produce Eumelanin or Pheomelanin? Or is this not important? I'm confused but know eumelanin is what is skin-protecting in darker skins.



Just re-read this and it sound like I'm waffling please excuse my chain of thought!

Just realised how much I begrudge the sun putting its hat on but at least he is slightly protected!
No problemo...will troll through my old reference literature and see if I can find the study taken and post for you
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  (#85) Old
Geeklin
Melanotans head weighs 8lbs
Posts: 51
Join Date: Oct 2008
Location: California
28-10-08, 08:07 PM

Melanotan one has at least twice been clinically shown to increase the body's production of eumelanin. The first study reported however that two individuals had a concurrent increase in pheomelanin expression (>50% increase), one with no UV exposure and the other only after UV exposure. The study also noted that based upon those two individuals' results that an avenue of possible research in terms of redheads' ability to possibly produce more eumelanin in favor of pheomelanin beckoned.
The second study looked at melanotan one's effect in individuals with variant MC1R genotypes (ie: redheads with certain variant alleles) and reported, "MELANOTAN one increased the melanin density to a greater extent in individuals carrying the variant alleles Val60Leu, Asp84Glu, Val92Met, Arg142His, Arg151Cys, and Arg160Trp than in individuals with no variant alleles."

Anecdotally there have been a number of ginger haired folks in the melanotan.org forum who've shared photos of themselves before and after using melanotan II that have shown a quite noticeable browning of their hair.

-Scott
Melanotan.org Admin

Last edited by Melanotan; 28-10-08 at 08:28 PM. Reason: sig
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  (#86) Old
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29-10-08, 08:28 AM

Thanks Collin and Melanotan. Think I'll have a peek at the photos!

Just looked and am even more put off I read the side affects (skin thickening without collagen and elastin increase, wrinkles, increase in moles, puffy eyes to name a few) some are claiming to suffer plus the need for sun beds/exposure to tan. It may only be useful (in my opinion) for those who are sun bed addicts to wean them off excessive use as they will have skin damage anyway.

Last edited by weezie; 29-10-08 at 09:02 AM.
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  (#87) Old
Geeklette
tonyv is not bad. They're just drawn that way
Posts: 10
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Location: stockton on tees
tanning injections Illegal??? - 29-10-08, 12:30 PM

Hi I have personally done no research on this subject but had heard that the injections had been banned in Australia and the USa due to adverse side effects some of which have been said to include blindness, we do have a client of our salon who had bought some injections from ebay after 5 of them the results to her facial skin was appalling, blotchy patchy we had to advise her to stop and used a course of micro derma braision to bring her skin back to some sort of normality

i would not know where to do the research to see if it has been banned in the usa and aus, but certainly would recomend that prior to even considering it, not that we ever would as there are just to many issues without the rumours that i have heard
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  (#88) Old
Geeklin
Melanotans head weighs 8lbs
Posts: 51
Join Date: Oct 2008
Location: California
29-10-08, 02:37 PM

Quote:
Originally Posted by tonyv View Post
i would not know where to do the research to see if it has been banned in the usa and aus, but certainly would recomend that prior to even considering it, not that we ever would as there are just to many issues without the rumours that i have heard
Sorry but from what you are describing (in particular anything about "ban" and/or "blindness") you appear to be confusing the melanotan peptides with something else and muddling this discussion. Please do the due diligence on this and either cite something or understand the terminology because at this rate you're only going to unhelpfully confuse the topic here. Neither melanotan one or melanotan II are illegal to use. Companies in the U.S. (and I imagine Australia as well) can legally sell either peptide so long as they do not make claims about what they do and so long as they are sold for non-human research. There are a number of companies that are actively selling the peptides in the U.S. As well there are no reports of either peptide causing blindness. Kindly inform yourself fully and when possible provide citations for what you are talking about.

Thanks,

-Scott
Melanotan.org Admin

Last edited by Melanotan; 29-10-08 at 02:45 PM.
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  (#89) Old
Geeklin
Melanotans head weighs 8lbs
Posts: 51
Join Date: Oct 2008
Location: California
29-10-08, 06:56 PM

Quote:
Originally Posted by weezie View Post
skin thickening without collagen and elastin increase
weezie,

Now studies have shown that usage of the peptides can cause thickening of the outer layer of skin (epidermis) by as much as 3 times nominal (original) thickness but where are you getting this information with regards to collagen and elastin? Is that personal conjecture? Aside from the additional melanin this epidermal thickening is part of the reason the researches think that melanotan one is effective as a photoprotective (the logic is that a thicker epidermis + melanin = thicker layer for more effective UVA + UVB blocking).

-Scott
Melanotan.org - afamelanotide Founder & Admin

Last edited by Melanotan; 24-09-09 at 02:52 PM.
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  (#90) Old
Newbie geek
icclestaces head weighs 8lbs
Posts: 4
Join Date: Feb 2007
Location: Rochdale
29-10-08, 07:04 PM

Well i used to have the odd sunbed and ued to burn slightly but since using Melanotan 2 and only having a 4 min sunbed session every few weeks i now dont burn at all and on my holiday in greece in 40oc heat again no burning, surley this is a positive thing. i know approx 20 plus people on melanotan and to be honest some of them looked a little freckly/patchy in the first few days but when the course was complete this subsided and they all look good. the scary thing is that young girls could order this off the internet with no clue on how to inject it and may abuse it i.e taking more that the required dosage with the thinking they would go darker faster. I was fine with the injecting as i have a nursing backround but know a few thin people who have injected into muscle and caused a bruise. have also found that men seem to tan in only 7days even fair skinned men, my boyf uses it and he is a enviable colour and its true that it increases libido in men and causes the odd spontenious erection but these effects do subside
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