Arthritis sufferers can have very painful joints so twisting fingers could be very uncomfortable but not necessarily.
Diabetes sufferers are slow to heal, can have circulation problems and maybe immune deficiency issues.
There are many variations and degrees of both conditions. If you are unsure then don't. Clients with such conditions usually know more about what can and can't be done.
Common sense and care are what is needed. Understanding of what you are doing and the various options are essential
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