I think it's definitely worth checking, especially for something like a home salon where you will have people visiting your house on a regular basis as part of the day-to-day running of your business.
And, as people have already said, the main stumbling blocks would be:
(1) The deeds of the house - particularly with regards to any "Restrictive Covenants" that may have been placed on the deeds, normally by the property developer. Common restrictive covenants include things like not allowing animals on the property, not letting you park a caravan or mobile home outside your house down to silly things like not letting you have a Sky TV dish on your wall! Not letting you run a business from your house is one that often pops up too
(2) The terms of the mortgage - you would need to speak to your mortgage provider about this.
(3) The terms of your buildings/contents insurance - you would need to speak to your insurer about this. In some cases, it may just be that anything to do with your business isn't covered by your home contents insurance policy, in which case you'd get commercial insurance cover for your salon equipment etc.
(4) The local council - they may want to start charging you Business Rates on your house (which are probably more expensive than Council Tax) if they think that a large part of your property is being used for business use - probably won't be a problem if it's just a single room being used for a home salon though.