Remeber Mani.Q is not a mixture or hybrid product, it is a true gel, so yes there is no reason you cant infill, Personally I just buffed the product down so it was almost transparent (the same as how it would look after 1 coat of colour), and filled, just like a regular infill, my first coat of colour i applied just to the fill area and my second coat i applied to the entire nail, other people may do this different to me but this is the way thats working for me.
Just have a bash and a play with your own nails, theres so much you can do with the Mani.Q, glitter, art, marbelling effect etc etc
Its soooooo much fun hehe
xxx